Thursday, August 31, 2006

Education in Germany

Biomedical Engineering in Germany

In Germany the educational system is divided into 3 classes

a)Techniche Hochschule – Technical University
These are the highest graded universities in terms of funding and also research publications. They are the best technical institutes in Germany.

b)Universität – University
These are the next grade of universities after technical universities. Well they are not mainly associated with technical subjects rather concentrate on not technical subjects.

c)Fachhochschule – University of Applied Sciences
These are the low profile institutes whose primary objective is to train students for industrial work. They don’t concentrate much on the research aspects and thus it is very difficult to get a PhD position after graduating from these institutes (Unless you are certified by a University).

Medium of Instruction

The international programs are in English. But in some Universities and Fachs the medium of Instruction can be a mixed one like say 80% English and 20% German or any other combination as such most of the courses will be in English itself. Where German is required most of the universities have a provision for the language course (either paid or free depends upon the individual institution and funding aspects)

Course Fees

Previous to 2004 the education was a fundamental right in Germany and thus was exempted from semester fees to make education available to all. The Government of Germany paid for all the educational expenses. But after 2004 there were serious financial problems with the German government and the research took a back step. In order to counter that and collect funds for the research the Universities were granted rights to charge for the education. So from 2004 many programs in the university are paid programs. The fees vary from 600€ to 24000€ a semester.

So before applying check out whether the program is free of cost or paid one.

Living Expenses

The students require funds for the following
a)Accomadation : 100€ - 300€ (If you share with others than the price is one the lower side while single rooms cost around 200-280€ depending on the area. If you stay outside the main city you will get rooms much cheaper).
b)Student Insurance : AOK charges 57€ a month and that is the same with TK. These are the two major insurances for the students. TK don’t provide insurance for the ambulance service while AOK is valid in 16 European countries, So check out the provisisons before signing in with the insurance company. Also remember that if you have not visited a doctor for the whole year you were paying the premium, you can claim a refund, wherein a calculated amount will be refunded. The insurance companies will not let you know this so clarify with them.
c)Food and other expenses – 100-300€ depending on the life style of the individual.

University of Technology, Aachen

MSc in Biomedical Engineering at University of Technology, Aachen (RWTH-Aachen)

The key study areas contained in this two year, interdisciplinary degree course reflect the characteristic Aachen profile in research in the area of Biomedical Engineering. The faculties for Mathematics, Computer Science and Natural Science, Mechanical Engineering, Electrical Engineering and Information Technology and also the Medical Faculty are involved in the courses specially devised for this Master’s degree course. Overall control rests with the Medical Faculty. The courses are held exclusively in the English language.

The program here is for 24 months with the last 6 months being for the Master Thesis. There is only winter intake which starts from Oct. Remember if you have a bachelor in Biomedical Engineering you have less chances of making into it as they prefer students from other areas to get specialized in Biomedical.

The course here is conducted in the university hospital which has an advantage and a disadvantage. The advantage is that you get live experience of dealing medical equipments and the medical communication to the docs is at the highest level. The disadvantage is that that docs are going to take up the medical courses and they can never satisfy an engineer hahahhahha. The other advantage of being admitted to this uni is the proximity to the Helmholtz Institute. The Helmholtz Institute is the one of the biggest research labs in Germany. The Institute hosts Philips Institute of Medical Information (opening the door for you into Philips), Institute of Biomaterials and Institute for Cardiovascular technologies. The Cardiovascular research lab is one among the 6 such institutes across the globe. So the added advantages of being in this university is great and that has to be utilized.

You can visit the official page of the program at www.masterprogramme.ukaachen.de
Or contact Dr. Karin Renner
Dekanat der Medizinischen Fakultaet
Pauwelsstraße 30
52074 Aachen
Germany
Phone: +49 (0) 241 80 85 541
E-mail: bme@ukaachen.de

University of Applied Sciences Luebeck

MSc in Medical Technology at University of Applied Sciences, Luebeck

Though this course is at a Fachhochschule the University of Luebeck certifies the course and thus you get a university degree at the end of the course. Course of study is jointly offered by the "Fachhochschule Luebeck" (Luebeck University of Applied Sciences) and the "Universität zu Luebeck" (University of Luebeck). Final degree is allocated by these two universities jointly

The Degree offered is Master of Science in Biomedical Engineering. This is a 3 semester (18 months) course which is completely offered in English. The course work of this program is Sponsored by the DAAD (German Academic Exchange Service).
The course work is specifically designed for engineers. The presence of Draeger in the region which is a subsidiary of Siemens also adds value to the program. The students can also try to apply to the Boston unit of this company which is actually engaged in the research. There are also some good labs in neuroengineering at University Luebeck.

You can have more information about this program at www.mt-master.com or send an e-mail to info@mt-master.com

University of Applied Sciences, Aachen

Master of Science in Biomedical Engineering at University of Applied Science, Aachen (Juelich campus)

The course starts during summer semester (April) and is for 24 months with last 6 months for master thesis. This program is sponsored by DAAD (DAAD is the official education representative body for the Government of Germany). The language of Instruction is completely English.

The program at fh-aachen is conducted at Juelich. It is a small place mainly famous for Forschungszentrum Juelich (Research Center, Juelich). This place has originally selected was selected for nuclear research, but then when Germany decided not to go Nuclear the super computers and other stuffs were diverted to sole developmental research purposes. Most of the students of FH-Juelich do their master thesis or part time jobs at this research center.

Further Information about admission is available at www.fh-aachen.de/masters.html or from
M.Sc. in Biomedical Enginerring
Aachen Universoty of Applied Sciences
Juelich Campus
Ginsterweg 1
52428 Juelich
Germany
Email : biomedmaster@fh-aachen.de
Phone : +49 (o)2461/99-3270 or - 3290

University of Applied Sciences, Furtwangen

MSc in Biomedical Engineering at University of Applied Sciences, Furtwangen

The language of Instruction is completely English, though some additional courses may be in German but then the courses required for the degree are in English. The course is of 3 semeter with the Winter Semster application deadline on 15th may.

The entry requirements are a University degree or equivalent as well as excellent English and German Skills. There is no Tuition Fees for this program.

The course director is Prof. Dr. Knut Möller.
For futher information contact at bme@hs-furtwangen.de

Furtwangen University of Applied Sciences
Computer Science, Engineering, B
Business, Media

Campus Schwenningen
Jakob-Kienzle-Str. 17
78054 Villingen-Schwenningen
Deutschland
Phone +49 7720 307 4251
Fax +49 7720 307 4207

University of Hannover

Master of Science in Biomedizintechnik at University Hannover

The course work at this university is for 3 semsters and offered in german. The program is conducted under the faculty of Mechanical Engineering.

The advantages of this University is the presence of the following research institutes
a)Zentrum für Biomedizintechnik (ZBM) – Center for Biomedical Technology
b)Mechatronik Zentrum Hannover (MZH) – Mechntronic center Hannover
c)Produktionstechnischen Zentrum Hannover (PZH) – Production center Hannover
d)Laser Zentrum Hannover (LZH) – Laser Center Hannover

The presence of the these institute make research more interesting and also easy to find a postion for a part time job or for Master Thesis.

For more information on the program contact

Fakultät für Maschinenbau
Studiendekanat und Studienberatung
Im Moore 11b, 30167 Hannover
Sprechzeiten
vormittags oder nach Vereinbarung
Tel. 0511 / 762-41 65, Fax -199 76
studiendekan@
maschinenbau.unihannover.de
www.maschinenbau.uni-hannover.de

Fachinformation zum Studiengang
Zentrum für Biomedizintechnik (zbm)
der Leibniz Universität Hannover
Fakultät für Maschinenbau
Sprecher:
Prof. Dr.-Ing. Dr.-Ing. E. h. mult. Dr. med.
h.c. Haferkamp
Lise-Meitner-Str. 1
D-30823 Garbsen / bei Hannover
Tel.: +49 (0)511 762-9815
Fax: +49 (0)511 762-9899
E-Mail: zbm@zbm.uni-hannover.de
Internet: www.zbm.uni-hannover.de
Beratung (ggf. Termin nach Vereinbarung):
Dipl.-Ing. T. Fabian
(0511) 762 –9842
fabian@iw.uni-hannover.de

Other Institutes..

MSc in Biomedical Engineering at University of Applied Sceinces, Muenster

The progarm is in german.

contact the following persons on more information about the program.

Prof. Dr. rer. nat. Thomas Rose – rose@fh-muenster.de
Prof'in. Dr. rer. nat. Karin Mittmann – mittmann@fh-muenster.de
www.fh-muenster.de/fb11.
Phone :02551 962166

FH Münster / Steinfurt
Fachbereich Physikalische Technik
Stegerwaldstraße 39
48565 Steinfurt


MSc. in Biomedical Engineering at Anhalt University of Applied Sciences

This university also provides MSc in Biomedical Engineering under the faculty of Eletrotechnik. The Studienkolleg (preparatory college for university studies) of the Anhalt University of Applied Sciences offers preparatory language courses and prepares students for admission at a German university.

The Website of this university is nor very helpful and thus could not provide with the course work but then I will try to update this as soon as possible.

MSc in Biomedicine and MSc in Biomedical Chemistry at University of Mainz also known as Johannes Gutenberg University, Mainz


The Biomedicine course ai with the faculty of Biology while the Biomedical Chemistry course is with the faculty of Chemie, Pharmazie und Geowissenschaften. Students of this course become qualified in drug research. Pharmaceutical courses are included alongside chemical and biochemical aspects.

Language of instruction: German, some courses are given in English
Standard Period of Studies: 4 semesters
Start of Studies: October (Winter Semester) Enrolment:
University approx. 31,500
Biomedicine starts in Winter semester

for further information contact

Univ.-Prof. Dr. Jürgen Markl
Johannes-von-Müller-Weg 6, Zi. 01-235
D 55099 Mainz
Tel +49 6131 39-22314
markl@uni-mainz.de
Sprechzeiten: Do 11-13 h

BSc in Medical Informatics and Biomedical Engineering at University of applied sciences, Stralsund

This is a bachelors program in german.

contact the following person for more information about the program

Prof. Dr. sc. hum. Hans-Heino Ehricke
Softwaretechnologie/Computergrafik
Fachbereich Elektrotechnik und Informatik Büro
Haus 4, Raum 331a
Fon +49 3831 456674
Fax +49 3831 456687
Fax per E-Mail +49 3831 45711674
E-Mail: Hans.Ehricke@fh-stralsund.de

Monday, August 28, 2006

Chronology of Stem Cells

August 2006

Kazutoshi Takahashi of Department of Stem Cell Biology, Institute for Frontier Medical Sciences, Kyoto University, Kyoto 606-8507, Japan and Shinya Yamanaka from CREST, Japan Science and Technology Agency, Kawaguchi 332-0012, Japan published a paper in the cell journal claiming the induction of Pluripotent stem cell from mouse embryonic and adult fibroblast cultures by defined factors.

They stated that differentiated cells can be reprogrammed to an embryonic-like state by transfer of nuclear contents into oocytes or by fusion with embryonic stem (ES) cells. Little is known about factors that induce this reprogramming. They demonstrated the induction of pluripotent stem cells from mouse embryonic or adult fibroblasts by introducing four factors, Oct3/4, Sox2, c-Myc, and Klf4, under ES cell culture conditions. These cells, which we designated iPS (induced pluripotent stem) cells, exhibit the morphology and growth properties of ES cells and express ES cell marker genes. Subcutaneous transplantation of iPS cells into nude mice resulted in tumors containing a variety of tissues from all three germ layers. Following injection into blastocysts, iPS cells contributed to mouse embryonic development. These data demonstrate that pluripotent stem cells can be directly generated from fibroblast cultures by the addition of only a few defined factors.

This is one cool paper where they have shown the proof that differentiated stem cells can again be reprogrammed into stem cells.

July 19, 2006

President George W. Bush vetoed a bill which would have allowed Federal money to be used for research where stem cells are derived from the destruction of the embryo.

2006

Pasteur Institute scientists provide evidence that muscle stem cells might retain both template DNA strands during cell division, resulting in conservative rather than semiconservative DNA replication.

Semiconservative replication would produce two copies that each contained one of the original strands and one entirely new strand.
The deciphering of the structure of DNA by Watson and Crick in 1953 suggested that each strand of the double helix would serve as a template for synthesis of a new strand. However, there was no way of guessing how the newly synthesized strands might combine with the template strands to form two double helical DNA molecules. The semiconservative model seemed most reasonable since it would allow each daughter strand to remain associated with its template strand. That the semiconservative model was correct was verified by the Meselson-Stahl experiment and other even more revealing experiments that allowed for autoradiographic visualization of the distribution of old and new strands within replicated chromosomes.

2004-2005

Hwang Woo-Suk claims to have created several human embryonic stem cell lines from unfertilised human oocytes. The lines are later shown to be fabricated
Hwang Woo-Suk () (born 29 January, 1953) is a South Korean biomedical scientist.

He was a professor of theriogenology biotechnology Seoul National University (dismissed on March 20, 2006) who rose to fame after claiming a series of remarkable breakthroughs in the field of stem cell research. Until November 2005, he was considered one of the pioneering experts in the field of stem cell research, best known for two articles published in Science magazine in 2004 and 2005 where he fraudulently reported to have succeeded in creating human embryonic stem cells by cloning. Both papers have been editorially retracted after being found to contain a large amount of fabricated data. He has admitted to various lies and frauds.

On May 12, 2006, Hwang was "indicted on embezzlement and bioethics law violations linked to faked stem cell research."

2003

Dr. Songtao Shi of NIH discovers new source of adult stem cells in children's primary teeth

Researchers at the Whitehead Institute announced in 2003 that they had successfully used embryonic stem cells to produce haploid, male gametes. They found embryonic stem cells that had begun to differentiate into embryonic germ cells and then further differentiated into the male haploid cells. When injected into oocytes, these haploid cells restored the somatic diploid complement of chromosomes and formed blastocysts in vitro. The online edition of Nature Medicine published a study on January 23 which stated that the human embryonic stem cells available for federally funded research are contaminated with non-human molecules from the culture medium used to grow the cells.

Chronology of Stem Cells

2000s

Several reports of adult stem cell plasticity are published

Adult stem cells are undifferentiated found throughout the body that divide to replenish dying cells and regenerate damaged tissues. Also known as somatic stem cells, they can be found in children, as well as adults.

Research into adult stem cells has been fueled by their abilities to divide or self-renew indefinitely and generate a cell types of the from which they originate — potentially regenerating the entire organ from a few cells.

1998

James Thomson and coworkers derive the first human embryonic stem cell line at the University of Wisconsin-Madison.

A breakthrough in human embryonic stem cell research came in November 1998 when a group led by James Thomson at the University of Wisconsin-Madison first developed a technique to isolate and grow the cells when derived from human blastocysts.
James A. Thomson (born in Oak Park, Illinois) is an American developmental biologist who also serves as a professor of anatomy in the University of Wisconsin School of Medicine and Public Health and as the chief pathologist at the Wisconsin National Primate Research Center. Thomson is currently the scientific director at
WiCell Research Institute, Inc.. WiCell is the spinoff company of the Wisconsin Alumni Research Foundation (WARF) charged with licensing Thomson's patented stem cells. He is also a member of the Genome Center of Wisconsin at the University of Wisconsin-Madison.

1997

Leukemia is shown to originate from a haematopoietic stem cell, the first direct evidence for cancer stem cells.

Cancer stem cell theory is the theory that tumors arise from cells termed cancer stem cells that have properties of normal stem cells, particularly the abilities to self-renew and differentiate into multiple cell types, and that these cells persist in tumors as a distinct population that likely causes disease relapse metastasis
A normal stem cell may be transformed into a cancer stem cell through disregulation of the proliferation and differentiation pathways controlling it.

1995

President Bill Clinton signs into law the Dickey Amendment which makes it illegal for Federal money to be used for research where stem cells are derived from the destruction of the embryo.

The Dickey Amendment is the name of a piece of federal legislation passed by United States Congress, and signed by former President Bill Clinton which prohibits the
Department of Health and Human Services (HHS) from using appropriated funds for the creation of human embryos for research purposes or for research in which human embryos are destroyed. HHS funding includes the funding for National Institutes of Health (NIH) funding. Technically the Dickey Amendment is a "rider" to other legislation, which amends the original legislation. The rider receives its name from the name of the Congressman that originally introduced the amendment, Representative
Jay Dickey. The Dickey amendment language has been added to each of the Labor, HHS, and Education appropriations acts for FY1997 through FY2004. The wording of the rider is generally the same year after year. For FY2005, the wording prohibits HHS from using FY2005 appropriated funds for:
(1) the creation of a human embryo or embryos for research purposes; or
(2) research in which a human embryo or embryos are destroyed, discarded, or knowingly subjected to risk of injury or death greater than that allowed for research on fetuses in utero under 45 CFR 46.208(a)(2) and Section 498(b) of the
Public Health Service Act (42 U.S.C. 289g(b)) (Title 42, Section 289g(b), United States Code). For purposes of this section, the term "human embryo or embryos" includes any organism, not protected as a human subject under 45 CFR 46 (the Human Subject Protection regulations) . . . that is derived by fertilization parthenogenesis cloning, or any other means from one or more human gametes ) or human diploid cells (cells that have two sets of chromosomes, such as somatic cells).

Chronology of Stem Cells

1992

Neural stem cells are cultured in vitro as neurospheres

It has since been shown that new neurons are generated in adult mice, songbirds and primates, including humans. Normally adult neurogenesis is restricted to the subvetricular zone, which lines the lateral ventricles of the brain, and the dentate gyrus of the hippocampal formation.

Neural stem cells are commonly cultured in vitro as so called neurospheres - floating
heterogeneous aggregates of cells, containing a large proportion of stem cells.
They can be propagated for extended periods of time and differentiated into both
neuronal cells, and therefore behave as stem cells.

1981

Mouse embryonic stem cells are derived from the inner cell mass

Embryonic stem cells (ESCs) are stem cells derived from the inner cell mass of a blastocyst, which is an early stage embryo - approximately 4 to 5 days old in humans - consisting of 50-150 cells.

Embryonic stem cells were first derived from mouse embryos in 1981 by two independent research groups (Evans & Kaufman and Martin).

1978

Haematopoietic stem cells are discovered in human cord blood

Multipotent hemopoietic stem cells (MHSC) are stem cells found in the bone marrow. MHSC are the precursor cells which give rise to all the blood cell types of both the myeloid lymphoid lineages. This includes monocytes, macrophages, neutrophils, basophils, eosinophils, T-cells, B-cells, NK-cells, microglia, erythrocytes (red blood cells), megakaryocytes (e.g. platelets), and dendritic cells. As stem cells, they are defined by their ability to form multiple cells types and their ability to self-renew.

1968

The First Bone marrow transplant between two siblings successfully treats SCID (Severe combined immunodeficiency).

Chronology of Stem Cells

1963

McCulloch and Till illustrate the presence of self-renewing stem cells in mouse bone marrow. Ernest Armstrong McCulloch is a Canadian cellular biologist, best known for demonstrating – with James Till – the existence of stem cells.

McCulloch was born in Toronto and studied medicine at the University of Toronto. His experience in hematology, when combined with Till's experience in biophysics, yielded a novel and productive combination of skills and interests. Till was working in Ontario Cancer Institute which McCulloch joined in 1957. In the early, McCulloch and Till started a series of experiments that involved injecting bone marrow cells into irradiated mice. Nodules were observed in the spleens of the mice, in proportion to the number of bone marrow cells injected. Till and McCulloch called the nodules 'spleen colonies', and speculated that each nodule arose from a single marrow cell: perhaps a stem cell.

In later work, Till and McCulloch were joined by graduate student Andy Becker, and demonstrated that each nodule did indeed arise from a single cell.

1960s

Joseph Altman an independent researcher at MIT and Gopal Das present evidence of adult neurogenesis, ongoing stem cell activity in the brain; their reports contradict Cajal's "no new neurons" dogma and are largely ignored. Joseph Altman is accrediated with the discovery of adult neurogenesis, the creation of neurons at adult brain. Before this period it was believed that the brain cells mainly neurons donot have the regenerative property and thus there was a wide spread belief that neurons cannot be formed in adults which left the Altman discovery in sidelines. In the late 1990s, the fact that the brain can create new neurons even into adulthood was rediscovered. Altman Continued his research at purdue university. He is now retired.

Ramón y Cajal was born in Petilla de Aragón Navarrese enclave in Aragon. Ramón y Cajal attended the medical school of Zaragoza, from which he graduated in 1873. Ramón y Cajal's most famous studies were on the fine structure of the central nervous system.

Ramón y Cajal's most famous studies were on the fine structure of the central nervous system. Golgi found that by treating tissue with a silver chromate solution, a relatively small number of neurons in the brain were darkly stained. This allowed him to resolve in detail the structure of individual neurons and led him to conclude that nervous tissue was a continuous reticulum (or web) of interconnected much like those in the circulatory system. Using Golgi's method, Ramón y Cajal reached a very different conclusion. He postulated that the nervous system is made up of billions of separate neurons and that these cells are polarized. Rather than forming a continuous web, Cajal suggested that neurons communicate with each other via specialized junctions called "synapses", a term that was coined by Sherrington. This hypothesis became the basis of the neuron doctrine, which states that the individual unit of the nervous system is a single neuron. Electron microscopy later showed that a plasma membrane completely enclosed each neuron, supporting Cajal's theory, and weakening Golgi's reticular theory. However, with the discovery of electrical synapses (direct junctions between nerve cells), some have argued that Golgi was at least partially correct. For this work Ramón y Cajal and Golgi shared the Nobel Prize in Physiology or Medicine. Ramón y Cajal also proposed that the way grow is via a growth cone at their ends. He understood that neural cells could sense chemical signals that indicated a direction for growth, a process called
chemotaxis.

Saturday, August 26, 2006

Bioinformatics

Typically refers to the field concerned with the collection and storage of biological information. All matters concerned with biological databases are considered bioinformatics. Bioinformatics is the study of the inherent structure of biological information and biological systems. It brings together the avalanche of systematic biological data (e.g. genomes) with the analytic theory and practical tools of computer science and mathematics.

Bioinformatics is today seen as primarily applied to speeding up new drug discovery. But the other area that assumes increasingly higher significance is the application of IT to the entire life sciences sector- for the same purpose it is done in other industrial sectors- improving efficiency, reducing costs, wider access, etc. For example bio-diversity data management is an area that requires application of the best database design techniques and planning for data warehousing and data-mining. Knowledge management as applied to corporations will also become relevant in the scientific context to ensure that Indian scientists get relevant and timely information related to their research to help them network and collaborate to create new intellectual property.

In 2004-05, the Indian bioinformatics sector registered revenues of 22.2 million USD, of which about 40% was from the local market and the rest from the exports. India’s entry into the product patent regime in 2005 has boosted the bioinformatics sector in 2004-05. This sector is expected to have a major slice of the global bioinformatics pie in the next few years.

At present there are about 45 companies in this space mainly concentrated in southern cities in like Bangalore, Chennai and Hyderabad. Of these about 35 companies are involved in developing bioinformatics tools.

India has the potential to assume global leadership in genome analysis. India has several ethnic populations that are valuable in providing information about disease predisposition and susceptibility, which in turn can help in drug discovery. The Institute of Genomics & Integrated Biology (IGIB), New Delhi is in the process of developing a database of genetic profiles among diverse Indian populations in terms of ethnicity, demographics and ancestral roots.

LIMS tools, a big opportunity

With the new IPR regime in place, sponsors are looking at companies in India to outsource their work and this has opened up the market for Laboratory Information Management Systems (LIMS) tools. The market for LIMS products in India is picking up. At present, the market is estimated to be in the range of US$ 13.3-15.6 million and growing at a healthy rate of 30-40 per cent. In India, LabVantge, Ocimum Biosolutions, Persistent Systems and Agaram Industries are some of the leading players offering LIMS products to companies. Multinational biosuppliers such as Thermo Electron Corporation and Perkin-Elmer are also offering LIMS products in India.

Bioinformatics Companies in India

Ocimum Biosolutions

Ocimum Biosolutions is a life sciences R&D enabling company with three focus areas, BioIT, Microarrays and Research services. The Microarray division of Ocimum has been recently acquired from MWG Biotech. These include Catalog “OciChip”, Custom “OciChip” and microarray services.

The BioIT division of Ocimum Biosolutions provides key, ready to use reliable, cost-effective software solutions for the biotech/pharma industry with a suite of products such as Biotracker™, Toxchek™, Pharmatracker™, Genchek™, OptGene™, Nutrabase™, Genowiz™ and iRNAchek™, and an array of custom services including Data mining, Algorithm development, Gene identification, Multiple-platform software development, Database creation and manipulation, and tools for image analysis.

The Research services division provides molecular biology services like GMO testing, Nucleic Acid Purification, DNA extractions, Oligonucleotide synthesis and Gene synthesis.
Corporate Headquarters (India)
Ocimum Biosolutions, Ltd
6th Floor, Reliance Classic
Road No. 1, Banjara Hills
Hyderabad - 500 034. A.P., India

Phone: +91-40-6662-7200
Fax: +91-40-6662-7205
Email: hyd@ocimumbio.com

Bioinformatics Companies in India

Molecular Connections

Molecular Connections Private Limited is the pioneering in-silico discovery services company founded by professionals with proven expertise in drug-discovery, informatics and information technology.

Molecular Connections provides high quality, cost effective text mining, literature curation and annotation services as well as products. It has proven competencies to curate and annotate information from full text articles, patent documents and abstracts covering various areas of biology and chemistry. Molecular Connections has specific expertise in building knowledge-bases for rapidly growing genomics, proteomics and related areas. In addition, Molecular Connections has powerful tool development, database integration and effective data development visualization capabilities.

Molecular Connections works across various areas including protein interactions and pathways, protein target databases, chemical compound and reaction information, ADME Tox, clinical, diseases, drugs etc.
Corporate Office

Molecular Connections Private Limited
IInd Floor, Brigade MLR,
#50, Vani Vilas Road,
Basavanagudi,
Bangalore - 560 004
India

Ph: +91-80-51205016
Fax: +91-80-51208956
For employment opportunities mail to: hr@molecularconnections.com

Bioinformatics Companies in India

Jubilant Biosys Ltd. (JBL)

Jubilant Biosys Ltd. (JBL), a Bangalore-based company, is focused on providing innovative informatics and structure- directed drug discovery solutions to help accelerate the process of global pharmaceutical drug discovery.
With superior technologies, world class talent and cutting-edge research, they are committed to delivering high quality, cost effective solutions to aid customers in the process of drug discovery.

JBL, established in 2001, has graduated from being a leading provider of discovery knowledgebase to an integrated collaborator in global pharmaceutical early lead discovery. At JBL, over 600 scientists experienced in chemistry, biology, biochemistry, pharmacology and clinical areas, and domain- specific IT experts, strive to deliver cost-effective innovation, driven by speed and efficiency.
Bangalore

Jubilant Biosys Ltd.
#96, Industrial Suburb,
2nd Stage, Yeshwantpur,
Bangalore - 560 022,
India.
Tel.: +91 80 66628400

Mysore

Jubilant Biosys Ltd.,
28/A, Ist Floor,
New Kantharaj Urs Road,
Kempu Nagar, Mysore,
India.
Tel.: +91 82 14257171

Noida

Jubilant Chemsys Ltd.,
Registered office: 1A, Sec 16A,
Noida - 201301
India.
Tel: +91 120 2516601 thru 11
Fax: +91 120 2580033

contact@jubilantbiosys.com

Bioinformatics Companies in India

GVK BioSciences Pvt. Ltd

GVK BIO is part of the $500 million GVK conglomerate that has operations in infrastructure, services, manufacturing and power.

In Cheminformatics, Services include Molecular Modeling Studies, Lead Generation, Virtual Screening, ADME and Toxicological Property Prediction and Crystal Structure Prediction.

In Informatics, Services include DNA and Protein sequence Analysis, Protein Structure Analysis, Homology Modeling and Visualization Tools.

Corporate Office - India
GVK Biosciences Private Limited
#210, 6-3-1192
Kundanbagh, Begumpet
Hyderabad – 500016, India
Tel : +91 40 6661 9990
Fax : +91 40 6662 6885
hrinfo@gvkbio.com

Bioinformatics Companies in India

Strand Genomics

Strand builds scientific software for the mining of biological data and literature. Strand is a technology company, an IISc start-up. Strand, since its inception, has developed outstanding technologies and capabilities in data analytics and predictive modeling for drug discovery and development. Strand's Data mining platform is widely used in verticals like gene expression, pre-clinical, chemistry and healthcare at various pharmaceutical and biotechnology companies and research institutions. Strand has also developed tools for Oligo design, Microarray image analysis and executed several custom data analysis projects.

Strand Life Sciences has entered into a research collaboration with Elan Pharmaceuticals aimed towards supporting Elan’s drug discovery efforts. This collaboration allows Elan to access strand’s technologies and achieve customised solutions for internal research programmes. The agreement incorporates access to Strand’s extensive in silico technology portfolio including predictive modeling for efficacy and ADMET, custom library design, QSAR and pharmacophore modeling, structure based drug design, data and visual mining and consulting experience.

The contact Address of Strand Life Sciences is:

Strand Life Sciences
237, Sir C.V. Raman Avenue,
Rajmahal Vilas,
Sadashivnagar,
Bangalore 560 080
INDIA
Phone:+91-80-23618992, 23618993, 23618994, 23611349
Fax:+91-80-23618996
careers@strandls.com

Bioinformatics Companies in India

Tata Consultancy Services

The latest player in the Indian bioinformatics market is the country’s largest information technology company, Tata Consultancy Services (TCS).

Tata Consultancy Services (TCS), a leading Indian technology services company, has entered into an agreement with Congenia, a biotechnology start-up promoted by Italy’s Genextra Spa group. The Life Sciences R&D division of TCS will work on “P66”, a target protein identified by Congenia as a key protein involved in several age-related diseases and will develop optimised drug leads based on it. TCS will be using modules of its own product “Bio-Suite” to work on the target protein. The optimized lead molecules produced by TCS will be further developed by Congenia through animal trials and eventually human clinical trials.

Congenia, which is 100% owned by Genextra SpA, is a drug discovery company active in research and development in the fields of biotechnology, biomedicine and functional genomics with particular focus on cancer pathologies related to aging and degenerative cell disorders.

The company is developing therapeutic applications based on the Team scientific discoveries and leading edge position in the validation of new gene targets with the aim of becoming a leader in the development of therapeutics to treat the foremost age-related disorders:

- Atherosclerosis
- Diabetic retinopathy
- Emphysema
- Ischemic heart diseases

The company also looks foreward to demonstrade the possibility to use drugs aimed at similar targets in cancer therapeutics.

Congenia S.p.A.
Via dei Bossi, 2/a
20121 Milano
+39 02 36515110
+39 02 36515115 (fax)
congeniainfo@congenia.it

Bioinformatics Companies in India

Questar Bioinformatics

QUESTAR Bioinformatics Ltd (QBL), a startup by Gland Pharma is located in Hyderabad. The proteomics start-up from the drug major, Gland Pharma, has entered into a strategic alliance with AlphaGene Inc., the Woburn, Massachussets-based genomics company.

AlphaGene Inc. has entered into a collaboration to use bioinformatics technology from Questar Bioinformatics Ltd. to mine AlphaGene’s protein library. Questar will provide support for structure determination, pathway identification, and small molecule library development. Questar Bioinformatics will pursue development of functional proteomics (the understanding of the functions of specific proteins in the human body) on some of the promising leads already generated by AlphaGene.
AlphaGene has generated several leads in neurological diseases such as Parkinson's and Alzhiemer's, which defy cure and cancers of the colon and breast. The company wants QBL to pursue these leads, use the latest research capabilities and take them to the logical stage of a drug, diagnostic or method of treatment.

The company plans to recruit researchers for determining the protein structure, identification of specific markers and generate a library of information. Simultaneously, it will play an important role in enhancing the value of the intellectual property created by AlphaGene.

The contact Address of AlphaGene is
AlphaGene, Inc.
260 W. Cummings Park
Woburn, MA 01801
info@alphagene.com
781.933.4446 phone
781.933.5424 fax

The contact address of Gland Pharma limited is
Gland Pharma Limited
6-3-862 Ameerpet
Hyderabad - 500 016
Ph: +91-40- 5562 1010
Fax: +91-40-2340 2229
Email : gland@glandpharma.com

Bioinformatic Companies in India

Accelrys Inc.

Accelrys, Inc. is a leading provider of software for modeling, computation, simulation, and the management and mining of scientific data used by biologists, chemists, and materials scientists, including nanotechnology researchers, for product design as well as drug discovery and development. SciTegic, Inc. is a wholly owned subsidiary of Accelrys that has pioneered a new technology platform called “data pipelining” to process research discovery data with unprecedented flexibility.

Employees: 525+ worldwide
Key Locations:
San Diego, CA, USA: Corporate Headquarters & Center of Excellence
Cambridge, UK: European Headquarters & Center of Excellence
Bangalore, India: Center of Excellence
Sales/support offices in Boston, Paris, Tokyo

Key Products:
Discovery Studio: integrated, PC-based life science modeling and simulation for Linux/Windows
Materials Studio: integrated materials simulation on the PC Cerius2, Catalyst, Insight II,
QUANTA: modeling for UNIX / Linux workstations
Accord: cheminformatics suites
Pipeline Pilot: the SciTegic Enterprise Server platform

For opportunities in India contact on the following address:
Darshana Singhvi
Bangalore, India
Tel: +91-80-51102242
Fax: +91-80-51102247
Email: resume_india@accelrys.com
http://www.accelrys.com/about/careers/indiajobs.html